also known as CBD
Cannabidiol, also known as CBD is one of the two most important cannabinoid components of the cannabis plant, found in variable proportions depending on the strain. While in some it is minimal, in others it may be the most abundant, or it may be found in proportions more or less equal to THC.
The plant has some compounds that have a psychoactive effect (alteration of perception and modification of mood) and others do not. Among the former are delta-9-THC, CBN (cannabinol) and delta-8-THC, with different potencies and concentrations in the plant, the most powerful and abundant being delta-9-THC. These compounds are responsible for producing the effects sought by recreational users, ie "the trip."
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On the contrary, although CBD is a compound that acts on the central nervous system and is therefore psychotropic, it does not have the psychoactive effects of THC. On the contrary, it antagonizes the psychotomimetic (psychotic simile) effects that it produces.
Currently, CBD is the cannabinoid with the most beneficial effects for the treatment of some symptoms and diseases, and with the greatest therapeutic margin; that is, with mild side effects over a wide range of doses. In general, CBD is very well tolerated.
Therapeutic properties of CBD
The most important therapeutic properties of CBD, demonstrated with different quality of evidence, are:
anti-inflammatory
analgesic
neuroprotective
anticonvulsant
antioxidant
anti-nausea and antiemetic
antitumor
anxiolytic
antipsychotic
cravings reducer for heroin, cocaine and alcohol
immuno-modulator
These properties make CBD used in the treatment of multiple diseases, some of which are:
epilepsy
neurodegenerative diseases (for example, Alzheimer's, Parkinson's, and Multiple Sclerosis)
chemical dependencies
anxiety
psychosis
autism spectrum disorder
chronic inflammatory diseases such as chronic polyarthritis, Crohn's disease, inflammatory bowel disease,
accompanying chemotherapy
antitumor treatment
Beyond its therapeutic uses, in some jurisdictions, CBD is recommended as a dietary supplement.
Adverse effects of CBD
Among the adverse effects, generally mild to moderate, when CBD is used in therapeutic doses, feelings of fatigue, drowsiness, dry mouth, headaches, dizziness and decreased appetite may occur. In general, they improve with the reduction of the dose of CBD and disappear when the administration is suspended.
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